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fn ab45688  (Cell Signaling Technology Inc)


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    Cell Signaling Technology Inc fn ab45688
    Fn Ab45688, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 97/100, based on 3181 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/fn+ab45688/p38+MAPK+XP+Rabbit+mAb/10__2147_slash_dddt__s522318-34-101-103
    Average 97 stars, based on 3181 article reviews
    fn ab45688 - by Bioz Stars, 2026-09
    97/100 stars

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    other:

    Article Title: Xian Huang Fang Inhibits the PKCδ/MAPK Signaling Pathway to Attenuate Renal Tubular Epithelial Cell Senescence and Thereby Delay Renal Interstitial Fibrosis
    Article Snippet: MS detection parameters: Full MS/dd-MS2 mode; scan range: m/z 150–1200; resolution: 70,000 (Full MS), 17,500 (MS2); H-ESI source: spray voltage +3.2 kV (positive), −2.8 kV (negative); capillary temperature: 320 °C; NCE: stepped 35% and 50%. https://doi.org/10.2147/DDDT.S522318 Drug Design, Development and Therapy 2025:19 6992 Powered by TCPDF (www.tcpdf.org) Reagents and Antibodies TGF-β1 (0922209–1, Peprotech), FN (ab45688, Abcam), anti-GAPDH (60,004-1-1g, Proteintech), anti-vimentin (SC6260, Santa Cruz), anti-α-smooth muscle actin (α-SMA) (ab124964, Abcam), anti-Ki67 (ab16667, Abcam), antip-NF-κB p65 (3033, CST), anti-phospho-PKCδ (Tyr311) (#2055, CST), anti-PKCδ (9616T, CST), anti-p-JNK (sc-6254, Santa Cruz), anti-JNK (sc-7345, Santa Cruz), anti-p-ERK (sc-7383, Santa Cruz), anti-ERK (4695T, CST), anti-p-p38 (4511T, CST), anti-p38 (8690T, CST), anti-OAT3 (bs-0609R, Bioss), anti-AQP1 (ab168387, Abcam), anti-CHOP (sc7351, Santa Cruz), anti-ATP1B1 (15,192-1-AP, Proteintech), and HSPA5/BiP/GRP78 (sc-13539, Santa Cruz) were used.



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    Accumulation of profibrotic proteins in diabetic kidneys. ( a ) Staining for collagens I/III by PSR (Mann-Whitney U test, *** p = 0.0003, ** p = 0.002) (n = 8–13), <t>fibronectin</t> (FN) (** p = 0.001 between male groups, ** p = 0.006 between female groups) (n = 7–13) and collagen IV (Mann-Whitney U test, ** p = 0.002, * p = 0.025) (n = 5–10) by IHC showed comparable increases between male and female diabetic mice. Immunoblotting of kidney lysates for ( b ) FN (Mann-Whitney U test, *** p = 0.0004, * p = 0.048) (n = 7–19) and ( c ) Col 1α1 (Mann-Whitney U test, * p = 0.039 between male groups, * p = 0.036 between female groups) (n = 7–11) show similar increases in diabetic male and female mice.
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    Accumulation of profibrotic proteins in diabetic kidneys. ( a ) Staining for collagens I/III by PSR (Mann-Whitney U test, *** p = 0.0003, ** p = 0.002) (n = 8–13), <t>fibronectin</t> (FN) (** p = 0.001 between male groups, ** p = 0.006 between female groups) (n = 7–13) and collagen IV (Mann-Whitney U test, ** p = 0.002, * p = 0.025) (n = 5–10) by IHC showed comparable increases between male and female diabetic mice. Immunoblotting of kidney lysates for ( b ) FN (Mann-Whitney U test, *** p = 0.0004, * p = 0.048) (n = 7–19) and ( c ) Col 1α1 (Mann-Whitney U test, * p = 0.039 between male groups, * p = 0.036 between female groups) (n = 7–11) show similar increases in diabetic male and female mice.
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    Accumulation of profibrotic proteins in diabetic kidneys. ( a ) Staining for collagens I/III by PSR (Mann-Whitney U test, *** p = 0.0003, ** p = 0.002) (n = 8–13), fibronectin (FN) (** p = 0.001 between male groups, ** p = 0.006 between female groups) (n = 7–13) and collagen IV (Mann-Whitney U test, ** p = 0.002, * p = 0.025) (n = 5–10) by IHC showed comparable increases between male and female diabetic mice. Immunoblotting of kidney lysates for ( b ) FN (Mann-Whitney U test, *** p = 0.0004, * p = 0.048) (n = 7–19) and ( c ) Col 1α1 (Mann-Whitney U test, * p = 0.039 between male groups, * p = 0.036 between female groups) (n = 7–11) show similar increases in diabetic male and female mice.

    Journal: Scientific Reports

    Article Title: Both sexes develop DKD in the CD1 uninephrectomized streptozotocin mouse model

    doi: 10.1038/s41598-023-42670-5

    Figure Lengend Snippet: Accumulation of profibrotic proteins in diabetic kidneys. ( a ) Staining for collagens I/III by PSR (Mann-Whitney U test, *** p = 0.0003, ** p = 0.002) (n = 8–13), fibronectin (FN) (** p = 0.001 between male groups, ** p = 0.006 between female groups) (n = 7–13) and collagen IV (Mann-Whitney U test, ** p = 0.002, * p = 0.025) (n = 5–10) by IHC showed comparable increases between male and female diabetic mice. Immunoblotting of kidney lysates for ( b ) FN (Mann-Whitney U test, *** p = 0.0004, * p = 0.048) (n = 7–19) and ( c ) Col 1α1 (Mann-Whitney U test, * p = 0.039 between male groups, * p = 0.036 between female groups) (n = 7–11) show similar increases in diabetic male and female mice.

    Article Snippet: Samples were separated using SDS-PAGE, then immunoblotted using the following antibodies: collagen I α1 (Col Iα1) (1:1,000, Cedarlane), fibronectin (FN) (1:1,000, Abcam), and GAPDH (1:1,000, Millipore).

    Techniques: Staining, MANN-WHITNEY, Western Blot

    Antibody information.

    Journal: Current eye research

    Article Title: Simvastatin attenuates glucocorticoid-induced human trabecular meshwork cell dysfunction via YAP/TAZ inactivation

    doi: 10.1080/02713683.2023.2206067

    Figure Lengend Snippet: Antibody information.

    Article Snippet: Target Catalog no. Company Dilution ICC/IHC Dilution IB anti-YAP 14074S Cell Signaling Technology 1:200 anti-TAZ 4883S Cell Signaling Technology 1:200 anti-TGM2 ab421 Cell Signaling Technology 1:400 1:1,000 Cy3-anti-αSMA C6198 Sigma-Aldrich 1:400 anti-αSMA ab5694 Abcam 1:1,000 anti-GAPDH G9545 Sigma-Aldrich 1:80,000 anti-p-MLC 3675 Cell Signaling Technology 1:200 anti-FN ab45688 Abcam 1:500 Alexa Fluor ® 488 anti-Rabbit A-27034 Invitrogen 1:500 Alexa Fluor ® 594 anti-Mouse A-21203 Invitrogen 1:500 IRDye ® 680RD anti-Rabbit 926-68071 LI-COR 1:15,000 Open in a separate window Antibody information.

    Techniques: